This pro-liposome approach serves as a motivation for large-scale production of liposomes containing lipophilic medications at a low cost. When hydrated, it forms an isotonic liposomal solution. This method involves coating a medication and a lipid onto a soluble carrier to create a pro-liposome, which is free-flowing and granular. The number of bilayers and the size of vesicles influence the amount of drug encapsulation in liposomes, a crucial factor in determining their circulation half-life. Liposomes are composed of phospholipids and lipids, forming spherical or multilayered vesicles with a lipid bilayer structure in aqueous solutions due to self-assembly of diacyl chain phospholipids.
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